Insight Into the Relationship Between Gastroesophageal Reflux Disease and Asthma

Being very overweight puts you at risk of more asthma symptoms, and you’re more likely to need your reliever inhaler more often. In older people, being obese may be a factor in why they got asthma in the first place.

Controlling GERD may even help keep your asthma symptoms in check, so what initially seemed like a double dose of trouble can actually turn into a win-win situation. But in the last few decades, doctors have uncovered a strong link between the two conditions. According to the American Academy of Allergy, Asthma & Immunology, as many as 70 percent of all people with asthma also have GERD, which is more than twice the average rate. Also, GERD seems to increase the sensitivity of airways and worsen asthma symptoms. Learn about the triggers and treatment for allergic asthma and how an allergist can help you manage allergy and asthma symptoms.

Reliable assessment of this issue is hampered by the presence of various lacunae in most of the published studies. Hence it is essential to carefully examine the strength of data suggesting a link between asthma and reflux. This article critically analyses currently available literature on the subject (including published reviews, meta-analyses, and randomised clinical trials in the English language) and summarises valid conclusions that can be drawn; it also proposes a framework for future studies to resolve the issue. Medications to treat GERD fall into five major categories. The most commonly used category is the proton pump inhibiter (PPI) and includes such medications as omeprazole (Prilosec), lansoprazole (Prevacid), pantoproazole (Protonix), and esomeprazole (Nexium).

Alkhayat, K. and Mohamed, A., 2015.

The LES is a muscle at the bottom of the food pipe (esophagus). The LES opens to let food into the stomach. It closes to keep food in the stomach. When the LES relaxes too often or for too long, stomach acid flows back into the esophagus.

All of this surgery can be done through an incision in the abdomen (laparotomy) or using a technique called laparoscopy. During laparoscopy, a small viewing device and surgical instruments are passed through several small puncture sites in the abdomen. This procedure avoids the need for a major abdominal incision. H2 antagonists are very good for relieving the symptoms of GERD, particularly heartburn. However, they are not very good for healing the inflammation (esophagitis) that may accompany GERD.

This is particularly true of theophylline (Elixophyllin, Theo-24, Theocron). But don’t quit taking or change any asthma medications without getting your doctor’s OK first. Although research has shown a relationship between asthma and GERD, the exact link between the two conditions is uncertain.

Given the obesity epidemic and the aging of the population [6] this prevalence figure is likely to increase. Chest physicians generally acknowledge a link between oesophageal disorders and respiratory disease; however, this relationship is complex and may manifest in a variety of clinical entities. A comprehensive, recent article has documented a causal link between gastro-oesophageal reflux disease (GERD) and asthma, chronic cough and posterior laryngitis [1], but in contrast the nature and scope of the relationship between other lung diseases and GERD has not been fully evaluated. This article will review the current knowledge of these disorders. The prevalence of gastroesophageal reflux in asthma patients without reflux symptoms .

Effects of 24 weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life, and pulmonary function in adult asthmatic patients with acid reflux symptoms. In addition, you may be asked to undergo a 24-hour study of your esophagus with an acid-sensing indicator to determine the presence or amount of reflux. A “proton pump inhibitor” also can be used to markedly reduce stomach acid production for one or two months. If you have GERD-related asthma, this therapy should help reduce your asthma symptoms.

Your physician may also recommend medications to treat reflux or relieve symptoms. Over-the-counter antacids and H2 blockers may help decrease the effects of stomach acid. Proton pump inhibitors block acid production and also may be effective. If you have both GERD and asthma, managing your GERD will help control your asthma symptoms.

These data suggest that asthmatics with GER have heightened vagal responsiveness. This hypervagal responsiveness may be partially responsible for the airway responses to esophageal acid. All of these data support the possibility that a vagally mediated reflex is active. studied 109 asthmatics and 135 controls in a questionnaire-based, cross-sectional analytic study; 77% of the asthmatics had heartburn, 55% had regurgitation, 24% had difficulty with swallowing, whereas 37% of the group required at least one antireflux medication and 41% had reflux-associated respiratory symptoms during the prior week.

GERD or acid reflux symptoms are caused by the regurgitation of acidic liquid stomach contents back up into the esophagus. GERD, also known as acid reflux disease, occurs when acid from the stomach reaches the esophagus. Normally, the connection between the esophagus and the stomach is controlled by a one-way valve, but if that valve becomes too weak, or if the pressure from the stomach becomes too great, acid will flow in the wrong direction. Recognition of GERD as a potential aetiological factor has important treatment implications, especially since corticosteroids may worsen GERD and continue to be widely used for therapy of IPF despite a lack of definitive clinical trials [61]. Trials of therapy for GERD in patients with established IPF are limited to one retrospective case series [79] of four patients with IPF and documented GERD who were only treated with PPI, these patients stabilised or improved over a 2-3-yr period.

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